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Job opportunity in the SyCaP project
The SyCaP project is a currently on-going biomedical materials project in which DSM, TU/e, and MUMC+ collaborate to develop a polymer knee resurfacing implant. In this project we can offer a 2 Year Postdoctoral or Junior Researcher Position. A start-up company will be founded in 2020, and the opportunity to transition the position into the start-up company is likely to be possible.
We seek highly motivated, enthusiastic candidates with an MSc degree, and preferably a PhD degree, in Biomedical Engineering, Mechanical Engineering, Material Science, Biomedical Science or similar. Experience with mechanical tests and finite element simulations is preferred. The candidate must have strong communication skills and be a pragmatic team player. Commitment is essential and the candidate should have a keen eye for detail. Proficiency in written and spoken English is a must. Travel between Eindhoven University of Technology and Maastricht University Medical Center will be regularly required.
SyCaP: New implant matches natural cartilage
The SyCaP project aims to develop a novel non-degradable, compliant, mechanically-functional osteochondral implant. The properties should match those of native cartilage better than the metal implants currently used. Therefore, it is anticipated that the clinical outcome will be superior, providing prolonged pain relief and functional restoration. In addition, because it is more compliant, it should be less limited to the defect location and easier to use it in various locations inside the joint. Finally, the material should enable future MR-imaging.
Over the past 4 years, implant prototypes have been developed and assessed in large animal trials. Currently, effort is focused on translating the design of the implant from the goat application to the human application. Mechanical testing, biomechanical testing, and finite element (FE) simulations will be employed to verify the implant’s safety and performance in vitro prior to the start of human clinical trials. This type of testing possibly includes fatigue testing, wear testing, impact testing, and biomechanical testing using a knee joint simulator. FE simulations will be employed to evaluate the performance of the implant in silico. The candidate will be responsible for ensuring that testing is performed and documented according to a quality management system, to ensure that the generated data can be used to complete the implant’s design history file.
More information? Watch the SyCaP movie here.